Atom Philosophies of drug dosing of chemotherapy article

600-word article on how doctors choose the amount of a chemotherapy drug to give a cancer patient. Note the medicines of interest are conventional chemotherapy, not targeted therapy drugs. Alternative dosing strategies have been proposed in order to replace body-surface area BSA-based dosing. Dose banding, fixed dosing, proposed other “indirect” body-size measures involve lean body mass (LBM), ideal body weight (IBW), adjusted ideal body weight (AIBW), and body mass index (BMI). Talk about anything interesting. Note I am not interested in metronomic chemotherapy or anything on the timing of delivery, just quantity. Here are some articles to get started on:

http://ascopubs.org/doi/full/10.1200/jco.2012.44.2863 http://theoncologist.alphamedpress.org/content/12/8/913.full https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375356/

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